Update on the Genetics of Alcoholism

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261  Letter From the Acting Director [PDF]

263  Editors’ Note [PDF]

264  In This Issue [PDF]

266  Overview: Assessing the Genetic Risk for Alcohol Use Disorders [PDF]
Tatiana Foroud, Ph.D., and Tamara J. Phillips, Ph.D.

270  Genetics Primer [PDF]

274  Identifying Genetic Variation for Alcohol Dependence [PDF]
Arpana Agrawal, Ph.D., and Laura J. Bierut, M.D.

282  Using Genetically Engineered Animal Models in the Postgenomic Era to Understand Gene Function in Alcoholism [PDF]
Matthew T. Reilly, Ph.D.; R. Adron Harris, Ph.D.; and Antonio Noronha, Ph.D.

293  Epigenetics—Beyond the Genome in Alcoholism [PDF]
Bela G. Starkman; Amul J. Sakharkar, Ph.D.; and Subhash C. Pandey, Ph.D.

306  Identifying Gene Networks Underlying the Neurobiology of Ethanol and Alcoholism [PDF]
Aaron R. Wolen, Ph.D., and Michael F. Miles, M.D., Ph.D.

318  The Impact of Gene–Environment Interaction on Alcohol Use Disorders [PDF]
Danielle M. Dick, Ph.D., and Kenneth S. Kendler, M.D.

325  Bridging Animal and Human Models: Translating From (and to) Animal Genetics [PDF]
Amanda M. Barkley-Levenson and John C. Crabbe, Ph.D.

336  Genes Contributing to the Development of Alcoholism: An Overview [PDF]
Howard J. Edenberg, Ph.D.

339  Genes Encoding Enzymes Involved in Ethanol Metabolism [PDF]
Thomas D. Hurley, Ph.D., and Howard J. Edenberg, Ph.D.

345  Alcohol Dependence and Genes Encoding α2 and γ1 GABAA Receptor Subunits: Insights from Humans and Mice [PDF]
Cecilia M. Borghese, Ph.D., and R. Adron Harris, Ph.D.

355  Immune Function Genes, Genetics, and the Neurobiology of Addiction [PDF]
Fulton T. Crews, Ph.D.

362  Circadian Genes, the Stress Axis, and Alcoholism [PDF]
Dipak K. Sarkar, Ph.D., D.Phil.

367  Discovering Genes Involved in Alcohol Dependence and Other Alcohol Responses: Role of Animal Models [PDF]
Kari J. Buck, Ph.D.; Lauren C. Milner, Ph.D.; Deaunne L. Denmark, M.D., Ph.D.; Seth G.N. Grant, Ph.D.; and Laura B. Kozell, Ph.D.

375 Glossary [PDF]

378 Resources [PDF]